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1
NeMoFinder: dissecting genome-wide protein-protein interactions with meso-scale network motifs
August 2006
KDD '06: Proceedings of the 12th ACM SIGKDD international conference on Knowledge discovery and data mining
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Recent works in network analysis have revealed the existence of network motifs in biological networks such as the protein-protein interaction (PPI) networks. However, existing motif mining algorithms are not sufficiently scalable to find meso-scale network ...


Keywords: graph mining, network motif, protein-protein interaction network
2
Prediction of Protein Functions Based on Protein-Protein Interaction Networks: A Min-Cut Approach
April 2005
ICDEW '05: Proceedings of the 21st International Conference on Data Engineering Workshops
Publisher: IEEE Computer Society
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This paper presents an approach for prediction of protein functions based on protein-protein interaction networks. For the purpose of prediction, we not only consider the interactions of functionunknown proteins with function-known proteins but also ...


Keywords: protein function prediction, protein-protein interaction network, min-cut, heuristic method.
3
Graph spectra as a systematic tool in computational biology
May 2009
Discrete Applied Mathematics , Volume 157 Issue 10
Publisher: Elsevier Science Publishers B. V.
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We present the spectrum of the (normalized) graph Laplacian as a systematic tool for the investigation of networks, and we describe basic properties of eigenvalues and eigenfunctions. Processes of graph formation like motif joining or duplication leave ...


Keywords: Biological network, Foodweb, Graph evolution, Graph spectrum, Metabolic network, Neuronal network, Protein-protein interaction network, Spectral plot, Transcription network