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ABSTRACT

Web navigation plays an important role in exploring public interconnected data sources such as life science data. A navigational query in the life science graph produces a result graph which is a layered directed acyclic graph (DAG). Traversing the result paths in this graph reaches a target object set (TOS). The challenge for ranking the target objects is to provide recommendations that re ect the relative importance of the retrieved object, as well as its relevance to the specific query posed by the scientist. We present a metric layered graph PageRank (lgPR) to rank target objects based on the link structure of the result graph. LgPR is a modification of PageRank; it avoids random jumps to respect the path structure of the result graph. We also outline a metric layered graph ObjectRank (lgOR) which extends the metric ObjectRank to layered graphs. We then present an initial evaluation of lgPR. We perform experiments on a real-world graph of life sciences objects from NCBI and report on the ranking distribution produced by lgPR. We compare lgPR with PageRank. In order to understand the characteristics of lgPR, an expert compared the Top K target objects (publications in the PubMed source) produced by lgPR and a word-based ranking method that uses text features extracted from an external source (such as Entrez Gene) to rank publications.

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INDEX TERMS

Primary Classification:
  H. Information Systems
  H.3 INFORMATION STORAGE AND RETRIEVAL
      H.3.5 On-line Information Services
          Subjects: Web-based services

Additional Classification:
  H. Information Systems
  H.2 DATABASE MANAGEMENT
      H.2.8 Database applications
          Subjects: Data mining

General Terms:
Algorithms, Experimentation

Keywords:
link analysis, navigational query, pagerank, ranking