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Morphogenesis as an amorphous computation
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Proceedings of the 3rd conference on Computing frontiers table of contents
Ischia, Italy
SESSION: Novel computing paradigms table of contents
Pages: 53 - 64  
Year of Publication: 2006
ISBN:1-59593-302-6
Author
Arnab Bhattacharyya  MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA
Sponsor
ACM: Association for Computing Machinery
Publisher
ACM  New York, NY, USA
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ABSTRACT

In this paper, we present a programming language viewpoint for morphogenesis, the process of shape formation during embryological development. Specifically, we model morphogenesis as a self-organizing, self-repairing amorphous computation and describe a framework through which we can program large-scale shape formation by giving local instructions to cell-like objects. Then, using this programmatic perspective, we specify some example developmental processes and discuss the characteristics that make them suitable candidates for evolutionary variation and selection. Consistent with the theory of facilitated variation from evolutionary biology, we find that variation in developmental processes can be introduced and conserved due to the hierarchical organization of growth specification.


REFERENCES

Note: OCR errors may be found in this Reference List extracted from the full text article. ACM has opted to expose the complete List rather than only correct and linked references.

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J. Bard. Morphogenesis. Cambridge University Press, Cambridge, UK, 1992.
 
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M. W. Kirschner and J. C. Gerhart. The Plausibility of Life. Yale University Press, 2005.
 
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A. Kondacs. Biologically-inspired self-assembly of two-dimensional shapes using global-to-local compilation. International Joint Conference on Artificial Intelligence, 2003.
 
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C. Nüsslein-Volhard Gradients that organize embryo development. Scientific American, August 1996.
 
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I. Salazar-Ciudad, J. Jernvall, and S. A. Newman. Mechanisms of pattern formation in development and evolution. Development, 130:2027--2037, 2003.
 
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J. Slack. From egg to embryo. Cambridge University Press, Cambridge, UK, 1991.

Collaborative Colleagues:
Arnab Bhattacharyya: colleagues