| BetaWB: modelling and simulating biological processes |
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Summer Computer Simulation Conference
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Proceedings of the 2007 summer computer simulation conference
table of contents
San Diego, California
SESSION: Bioinformatics/biology: bioinformatics 1
table of contents
Pages 777-784
Year of Publication: 2007
ISBN:1-56555-316-0
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Authors
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Lorenzo Dematté
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University of Trento Centre for Computational and Systems Biology, University of Trento
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Corrado Priami
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University of Trento Centre for Computational and Systems Biology, University of Trento
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Alessandro Romanel
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University of Trento Centre for Computational and Systems Biology, University of Trento
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Downloads (6 Weeks): 1, Downloads (12 Months): 19, Citation Count: 2
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ABSTRACT
This paper presents BetaWB, a framework for modelling and simulating biological processes. The modelling language is based on β-binders, a process calculus developed for better representing biological interactions. In order to provide efficient and accurate stochastic simulation, a new stochastic selection algorithm, based on the Gillespie assumption, is presented. Moreover, two companion graphical tools for the model development and simulation results analysis are provided.
REFERENCES
Note: OCR errors may be found in this Reference List extracted from the full text article. ACM has opted to expose the complete List rather than only correct and linked references.
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L. Cardelli. Brane calculi. In V. Danos and V. Vincent Schächter, editors, Computational Methods in Systems Biology, International Conference CMSB 2004, Paris, France, May 26--28, 2004, Revised Selected Papers, LNCS, pages 257--278. Springer, 2005.
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P. Degano, D. Prandi, C. Priami, and P. Quaglia. Beta-binders for biological quantitative experiments. In 4rd Int. Workshop on Quantitative Aspects of Programming Languages (QAPL 06), 2006. to appear.
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D. T. Gillespie. Exact stochastic simulation of coupled chemical reactions. J. Phys. Chem., 81(25):2340--2361, 1977.
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A. Phillips and L. Cardelli. A Correct Abstract Machine for the Stochastic Pi-calculus. In BioConcur '04, Workshop on Concurrent Models in Molecular Biology, 2004.
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C. Priami and P. Quaglia. Beta binders for biological interactions. In CMSB, pages 20--33, 2004.
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A. Regev and E. Shapiro. Cells as computation. Nature, 2002.
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A. Regev, W. Silverman, and E. Shapiro. Representation and simulation of biochemical processes using the pi-calculus process algebra. In Proceedings of the Pacific Symposium of Biocomputing 2001, volume 6, pages 459--470, 2001.
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A. Romanel, L. Dematté, and C. Priami. The Beta Workbench. Technical Report TR-3-2007, The Microsoft Research - University of Trento Centre for Computational and Systems Biology, February 2007.
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V. Volterra. Variazioni e Fluttuazioni del Numero d'Individui in Specie Animali Conviventi, pages 1--110. Memorie dela R. Academia Nationale dei Lincei. 1926.
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